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Tyrosine Supplement May Shorten Men's Lifespan, Study Suggests

Elevated blood tyrosine levels are associated with reduced male life expectancy

Daniele Morais
September 7, 2026 · 3 min read
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Tyrosine Supplement May Shorten Men's Lifespan, Study Suggests
Photo: "Spirillum Bacteria" by adonofrio (Biology101.org) is licensed under CC BY 2.0. To view a copy of this license, visit https://creativecommons.org/licenses/by/2.0/.

A large-scale study, involving over 270,000 participants, found an association between elevated blood tyrosine levels and a decrease in men's life expectancy. The analysis combined observational data with genetic research, indicating that the amino acid could reduce male longevity by almost a year.

Sources of Tyrosine in the Diet

Tyrosine is an amino acid naturally found in protein-rich foods such as meats, dairy products, and legumes. Additionally, the compound is marketed as a dietary supplement, promoted to improve focus and mental performance.

Gender Differences

The results indicate that while men show a reduction of almost one year in life expectancy associated with increased tyrosine, women do not demonstrate a significant effect. This difference in impact between sexes was observed in both observational and genetic analyses.

Implications for Supplement Consumption

The finding suggests caution when considering tyrosine supplement intake, especially among men, as the association with shorter longevity may represent a potential risk. The study does not indicate direct causality but highlights the need for careful evaluation of blood levels of this amino acid when considering supplementation for cognitive purposes.

  • Study with >270,000 people.
  • Elevated tyrosine linked to ~1 year shorter lifespan in men.
  • No significant effect in women.
  • Tyrosine is present in protein-rich foods and as a supplement.

With information from ScienceDaily.

Source: ScienceDaily

#health#nutrition#supplements#research#longevity
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