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NFL: Week 1 approaches with big matchups and betting market

The American football season is about to start, with the Week 1 schedule and the first analyses already moving fans and bettors.

Daniele Morais
September 2, 2026 · 3 min read
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NFL: Week 1 approaches with big matchups and betting market
Photo: "CINvLOU 2018-05-26 - Nippert Stadium crowd (28502599168)" by Hayden Schiff from Cincinnati, USA is licensed under CC BY 2.0. To view a copy of this license, visit https://creative

Anticipation for the NFL season kickoff is high, and the search for “nfl schedule this week” reflects the enthusiasm of fans and bettors. With Week 1 about to begin, the game calendar and the first analyses are already stirring the sports scene, promising big matchups and betting opportunities.

The season start and the opening game

The NFL season is approaching, and Week 1 already has a date set for its kickoff. The first clash will be between the New England Patriots and the Seattle Seahawks, scheduled for Wednesday, September 9, at Lumen Field. This game is a rematch of Super Bowl LX, adding an extra layer of rivalry to the season opener.

Featured matchups in Week 1

Besides the opening showdown, Week 1 of the NFL promises other intriguing duels. Among them are divisional battles such as the Chiefs vs. Broncos and the Cowboys vs. Giants. Other games generating interest include the Steelers vs. Falcons, with a nod to Aaron Rodgers’ “last outing,” and the Dolphins vs. Raiders, which will feature the debut of two new starting quarterbacks, with Miami’s Malik Willis dueling Kirk Cousins. The Jaguars, meanwhile, will host Cleveland on Sunday, while the Eagles will meet the Commanders also on Sunday.

Predictions and analyses for the games

Advanced computer models have already simulated Week 1 games, providing betting forecasts. One model indicates the Jaguars should cover the spread at home against Cleveland, with a probability of nearly 60%. It also predicts the total points (Over) will be hit in 63% of simulations for that same game. For the Eagles vs. Commanders clash, the model shows the Eagles should cover the spread in almost 60% of simulations. Philadelphia has a recent favorable record against Washington when Jalen Hurts is playing, and the Commanders’ defense, which was last in yards allowed last year, is in transition with up to eight new starters and a scheme change. The absence of Laremy Tunsil (triceps), the Commanders’ offensive tackle, and the expectation that Jayden Daniels will run less, are also factored in.

The betting market and odds movement

The anticipation of Week 1 has generated intense activity in the betting market, with many sites already adjusting odds. Differences in lines can be seen across platforms, potentially affecting bettors’ returns. For example, a wager on the Patriots may yield a higher profit on one site than another, and the same applies to bets on the Seahawks. Spread values also vary.

Major offseason player moves have also influenced the market. The Los Angeles Rams’ trade for Myles Garrett, Trent McDuffie and the return of Aaron Donald, who had retired, dramatically shifted Super Bowl odds, making the Rams the favorites. Patrick Mahomes’ recovery from an anterior cruciate ligament injury is another factor to watch, as Kansas City’s chances hinge on his early performance.

With information from CBS Sports, sports.betmgm.com, Bookies.com.

Source: CBS Sports, sports.betmgm.com, Bookies.com

#NFL#Week 1#American Football#Sports Betting#NFL Schedule#NFL Odds
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